How one man defied his genetic fate for nearly two decades

Scientists discovered a rare case of an Alzheimer’s gene carrier who remained symptom-free for 18 years beyond the expected onset, revealing potential genetic, environmental, and proteomic resilience factors. Study: Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia. Image Credit: Kateryna Kon / Shutterstock In a recent study in the journal Nature Medicine, … Read more

International travel and health care networks drive Candida auris outbreaks

In just a decade, the drug-resistant fungal pathogen Candida auris (C. auris) has emerged as one of the most formidable threats to health care settings worldwide. Nowhere in the United States is this threat more pronounced than the New York-New Jersey (NY-NJ) metro area, which accounts for nearly 20 percent of the nation’s cases. A … Read more

Study identifies new molecular target for treating keloids

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress. These scars are driven by an overproduction of extracellular matrix components like type I collagen, linked to an imbalance in tissue repair mechanisms. Current treatments show limited efficacy due to an incomplete understanding of the … Read more

Researchers uncover how PICH protein protects DNA during cell division

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer. Led by Professor Gary Ying Wai CHAN from the School of Biological Sciences, Faculty of Science, and Professor Ken Hoi Tang MA from the … Read more

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation. The cancer also has the potential … Read more

Study reveals route of entry for Semliki Forest virus into the brain

In a recent study, researchers from Uppsala University show that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain. This finding could potentially be used to develop the Semliki Forest virus as an agent for … Read more

CeVD-related brain network phenotype can provide insights into cognitive decline trajectory

Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer’s disease (AD) pathology to impact neurodegeneration and cognition in older adults. Led by Associate Professor Juan Helen Zhou, Director of the Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore … Read more

Stanford researchers develop AI model to enhance cancer prognosis predictions

The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care. But while artificial intelligence helps doctors review images and home in on disease-associated anomalies like abnormally shaped cells, it’s been difficult to develop … Read more

AI Speeds Up Diagnoses in China

AI Speeds Up Cancer Diagnosis⁣ in China A revolutionary AI-powered tool is transforming cancer diagnosis in China, offering a‍ potential solution ‍to a critical ​shortage ‌of skilled pathologists. ⁤developed by Zhejiang University, OmniPT is a universal pathology assistant that uses a combination ​of vision ‍and language AI to interact ​with human‌ experts, significantly improving both⁤ … Read more