Triglyceride-lowering drug olezarsen fails to reduce arterial plaque

Despite experiencing significant reductions in triglycerides, patients with triglycerides over 150 mg/dL and a high risk of atherosclerosis did not experience any significant change in the amount of non-calcified plaque in their coronary arteries after taking the triglyceride-lowering drug olezarsen, in a one-year sub-study presented at the American College of Cardiology’s Annual Scientific Session (ACC.26). … Read more

Low testosterone and high fructose intake can worsen fatty liver disease

Low testosterone in itself can cause a variety of health problems, but the addition of a poor diet can exacerbate certain conditions. Metabolic dysfunction-associated steatotic liver disease (MASLD) is one example that approximately 40% of adult men worldwide currently suffer from and has become a global problem. Fatty liver, the initial stage of MASLD, is … Read more

Red wine lowers bad cholesterol but doesn’t improve overall heart health

A sweeping meta-analysis reveals that while red wine may nudge down LDL cholesterol, its broader heart health benefits remain uncertain—reminding us that moderation and lifestyle still reign supreme. Review: The effects of wine consumption and lipid profile: A systematic review and meta-analysis of clinical trials. Image Credit: Lukas Gojda / Shutterstock Red wine has long been thought … Read more

A defense against Sepsis-Related mortality

New research reveals how fluoxetine boosts immune protection and prevents sepsis-related heart and metabolic damage. Study: Fluoxetine promotes IL-10–dependent metabolic defenses to protect from sepsis-induced lethality. Image Credit: luchschenF/Shutterstock.com In a recent study published in Science Advances, researchers showed that fluoxetine, a selective serotonin reuptake inhibitor (SSRI), promotes metabolic defenses to protect from sepsis-induced death. Background Sepsis … Read more

Your gut bacteria shape your health from childhood to old age, study reveals

Scientists uncover how your gut bacteria evolve over time—impacting weight, diabetes, and heart health—offering new insights into preventing metabolic diseases. Study: Association between gut microbiome profiles and host metabolic health across the life course: a population-based study. Image Credit: Tatiana Shepeleva / Shutterstock Did you know that over 1 billion people worldwide suffer from metabolic disorders like … Read more

TyG index linked to obesity measures can predict hypertension risk in US adults

Discover how a simple metabolic marker, the TyG index, combined with obesity measures, can help predict and manage hypertension risk in American adults—offering new hope for cardiovascular health. Study: Association of the triglyceride glucose index with obesity indicators and hypertension in American adults based on NHANES 2013 to 2018. Image Credit: Naeblys / Shutterstock In a recent … Read more