BREAKING: New Hope for Treating Mitochondrial Damage Table of Contents BREAKING: New Hope for Treating Mitochondrial Damage What We Know So Far targeting Mitochondrial Fission Uncovering a Vulnerable… The post Protect Mitochondria: Stress Damage Breakthrough appeared first on NewsyList. Source link
Summary: A groundbreaking experimental therapy for a rare, aggressive form of ALS caused by FUS gene mutations has produced surprising clinical improvements in some patients, including restored mobility and extended survival. The treatment uses antisense technology to silence the FUS gene, reducing toxic protein buildup in motor neurons. Two patients in a recent case series … Read more
Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer’s, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain’s blood vessels. University of Connecticut researchers report in the April 16 issue of Science Advances that mutations in the TARDBP gene that reduce TDP-43 protein levels also impair the cells … Read more
TOPLINE: Four serum neurofilament light chain (NfL) tests showed high accuracy in diagnosing and predicting progression of amyotrophic lateral sclerosis (ALS) in a new study. Investigators said the findings also offer diagnostic and prognostic cutoff values and lay the foundation for future use of the tests in clinical practice. METHODOLOGY: This study included 139 patients … Read more
Living in a disadvantaged community may decrease the length of time a person can survive with amyotrophic lateral sclerosis, or ALS, by over 30%, a Michigan Medicine-led study suggests. ALS is a progressive, incurable condition that causes muscle wasting and loss of muscle control. While most people survive with ALS around two to four years, … Read more