HbA1c

Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity

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Can combining two gut hormone pathways unlock better obesity treatments? In the first human trial of dapiglutide, researchers found encouraging metabolic signals but no statistically significant edge over placebo, highlighting both the promise and the limits of next-generation dual agonists. Trial: Dapiglutide, a dual GLP-1 and GLP-2 receptor agonist, for obesity: a randomised, double-blind, placebo-controlled … Read more

Syzygium jambolanum extract shows promise for diabetes management

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The search for effective and accessible therapies for diabetes continues to draw attention to medicinal plants with a long history of traditional use. A new study investigates the protective and antidiabetic effects of Syzygium jambolanum extracts, providing biochemical and clinical evidence supporting their role in improving glycaemic control and metabolic health. Traditional remedy under scientific … Read more

How GLP-1 drugs affect the body beyond weight loss and glucose control

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Widely used weight-loss and diabetes drugs show clear benefits, but emerging evidence clarifies their side effects, rare risks, and what clinicians should monitor long term. A recent review article published in the Journal of Clinical Investigation summarized the adverse effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual incretin receptor agonists such as tirzepatide. Of … Read more

PFAS exposure increases gestational diabetes risk

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A comprehensive review of nearly 130 studies shows the strongest evidence to date that “forever chemicals” are associated with gestational diabetes, while underscoring uncertainty around other diabetes outcomes and the need for more prospective research. Study: Associations of perfluoroalkyl and polyfluoroalkyl substances with markers of glycaemic control, insulin secretion and sensitivity, and diabetes risk: a … Read more

Digital lifestyle program cuts diabetes risk by 46% in prediabetics, study of 130k+ adults reveals

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Could a 45-minute weekly digital coach be the key to reversing diabetes? New study of 130k+ adults shows dramatic risk reduction and remission rates, without pills or extreme diets. Study: Lifestyle Modification in Prediabetes and Diabetes: A Large Population Analysis. Image Credit: RSplaneta / Shutterstock In a recent article published in the journal Nutrients, researchers in the … Read more

Study reveals hidden cardiovascular risks in real-world low-carb diets

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A new study reveals that while low-carb, high-fat diets may spare saturated fats and carbs from blame, high cholesterol and salt intake still threaten heart health—urging smarter food choices even in trendy diets. Study: Low carbohydrate high fat-diet in real life; A descriptive analysis of cardiovascular risk factors. Image Credit: 19 STUDIO / Shutterstock In a recent … Read more

Only 13% of French adults have optimal heart health—here’s what’s driving the gap

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Despite universal healthcare access, most French adults have sub-optimal heart health—but new research shows that even modest improvements in lifestyle could dramatically cut cardiovascular risk. Study: Life’s Essential 8 cardiovascular health status of 18-69-year-old individuals in France. Image Credit: Good dreams – Studio / Shutterstock Despite substantial advancements in medicine, cardiovascular disease remains a leading cause of … Read more

Hybrid closed-loop insulin pumps improve time in range, but increase ketoacidosis

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People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies*, insulin administration is manually controlled, while hybrid closed-loop systems* automatically regulate insulin delivery. A study with the involvement of the German Center for Diabetes Research showed that hybrid closed-loop systems offer improved long-term blood sugar values … Read more

Australia sees a decline in type 2 diabetes, but disparities persist

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New study reveals a decade-long decline in type 2 diabetes across Australia but warns of surges in younger men and specific ethnic populations, urging targeted prevention efforts. Study: Changes in the incidence of type 2 diabetes in Australia, 2005–2019, overall and by socio‐demographic characteristics: a population‐based study. Image Credit: Halfpoint / Shutterstock In a recent study published … Read more