Discovery of novel gene candidate sheds light on autism mechanisms

Autism spectrum disorder (ASD) is a condition affecting the brain’s development and often affects the ability of a person to perceive sensory information and social cues and socialize with others. Recent studies have revealed that environmental factors and epigenetic processes, such as DNA methylation, are crucial to the development of ASD. Notably, immune activation and … Read more

Ketogenic diet reverses obesity-linked biological aging by over 6 years

Obesity fast-forwards your biological clock—but science now shows a strict keto diet can roll it back. This breakthrough study reveals how shedding weight with VLCKD can actually slow or even reverse epigenetic aging by over six years. Study: Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following Very Low-Calorie Ketogenic Diet (VLCKD): A … Read more

AI approach reveals possible fusion of rare diseases in COVID-19 origins In A Landmark Dis…

Despite extensive research, the origins of COVID-19 remain elusive. In a new study published in the KeAi journal Advances in Biomarker Sciences and Technology (ABST), an AI-driven approach was adopted to examine DNA methylation patterns at 865,859 CpG sites in blood samples from early COVID-19 patients. The study was conducted by Zhengjun Zhang from the … Read more

Research shows epigenetic aging in the blood as potential breast cancer marker

A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) on December 5, 2024, Volume 16, Issue 22, titled “DNA-methylation age and accelerated epigenetic aging in blood as a tumor marker for predicting breast cancer susceptibility.” Researchers Su Yon Jung, Herbert Yu, Youping Deng, and Matteo Pellegrini … Read more

Androgen clock reveals how hormones shape aging and health

The androgen clock is rewriting the science of aging, offering a precise way to measure hormone exposure and its profound effects on health, longevity, and biology. ​​​​​​​Study: The androgen clock is an epigenetic predictor of long-term male hormone exposure. ​​​​​​​Image Credit: ivector / Shutterstock In a recent study published in the journal Proceedings of the National Academy … Read more

Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.  In the study, published Jan. 8 in the journal Nature … Read more