G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide range of physiological processes and are the targets of more than 30% of currently marketed drugs. The histamine H1 receptor (H1R) is one such GPCR subtype that … Read more
A new randomized trial shows that short bursts of supervised high-intensity exercise may retrain the brain’s fear response to bodily sensations, offering a scalable and engaging new therapeutic pathway for people with panic disorder. Study: Brief intermittent intense exercise as interoceptive exposure for panic disorder: a randomized controlled clinical trial. Image credit: Pixel-Shot/Shutterstock.com Interoceptive exposure … Read more
Neuropathic pain, caused by injury or disease of the somatosensory nervous system, is a major clinical… The post Electroacupuncture: Anxiety & Pain Relief – Neural Effects appeared first on Archynetys. Source link
Neuropathic pain, caused by injury or disease of the somatosensory nervous system, is a major clinical challenge and often evolves into a chronic condition. Importantly, up to 80% of patients with long-term pain also experience anxiety or depression. This creates a vicious cycle that not only worsens prognosis and quality of life but also poses … Read more
A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing how butyrate-a short-chain fatty acid produced by gut commensal bacteria-enhances T follicular helper (Tfh) cell activity to promote antibody production and strengthen mucosal vaccine efficacy. This study identifies a new microbiota–immune–antibody production axis linking microbial metabolism … Read more
The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, they sometimes come with severe long-term consequences. Since lymph nodes do not naturally regenerate once removed, their absence … Read more
Analyzing nearly 11.5 million births across four decades, researchers use rigorous methods to show that fluoridated drinking water is not linked to lower birth weight. Study: Community Water Fluoridation and Birth Outcomes. Image credit: Tatjana Meininger/Shutterstock.com While fluoridated water is widely considered a public health benefit, its potential association with reduced birth weight has often … Read more
A small but rigorous randomized trial suggests paracetamol may be a feasible alternative to ibuprofen for late PDA treatment, while underscoring the need for larger multicenter studies to guide neonatal care. Study: Paracetamol or ibuprofen? A pilot study comparing rescue therapy for PDA in preterm infants within the first month. Image Credit: Jana Kollarova / … Read more
Sleep problems are increasingly common among children and adolescents, affecting emotional regulation, cognitive development, and healthy conditions. As families are seeking quick and accessible solutions, melatonin supplements have gained widespread popularity due to their availability, child-friendly formulations, and perception as a safe, natural alternative to prescription drugs. Yet melatonin is a kind of hormone that … Read more
The PRoRota-project will use probiotics, improved education in hygiene and advanced mathematical models to prevent children from dying of diarrhea in low and middle-income countries. Diarrhea kills nearly two million lives every year and is one of the main causes of child deaths globally. Rotavirus is one of the most important causes of childhood diarrhea, … Read more