Groundbreaking research reveals how gut microbes and dietary soy can influence the outcome of cancer treatments, paving the way for a new frontier in personalized oncology. Study: Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Image Credit: CI Photos / Shutterstock In a recent study published in the journal Cell, researchers demonstrated that phytochemicals … Read more
Dengue fever caused by a flavivirus named DENV is a major global health challenge, risking almost half of the world’s population. Since the early 20th century, the scientific community has faced multiple challenges to develop effective dengue vaccines. This spanned a variety of techniques – from the use of ox bile to weaken DENV to … Read more
Music, light, and digital therapies show promise as safer alternatives to risky medications in easing dementia-related agitation, offering a potential path for some patients and caregivers alike. Story: Treatment of agitation in dementia – a systematic review. Image credit: RasaSopittakamol/Shutterstock.com Millions of people suffer from dementia conditions like Alzheimer’s disease. The occurrence of anxiety and distress … Read more
As researchers uncover the complexities behind cow’s milk allergy in breastfed infants, new evidence suggests that strict maternal dairy avoidance may not always be necessary, paving the way for more personalized and evidence-based management. Study: Cow’s Milk Allergy in Breastfed Infants: What We Need to Know About Mechanisms, Management, and Maternal Role. Image Credit: Pixel-Shot / … Read more
A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment. Researchers led by Ludwig Lausanne’s Helen Carrasco … Read more
Acute coronary syndrome (ACS) in patients with SARS-CoV-2 infection represents a critical intersection of viral-induced inflammation and cardiovascular pathology. This review explores the dual mechanisms driving SARS-CoV-2-associated ACS and evaluates emerging therapeutic strategies, including phytomedicine and nanotechnology, to address both viral and cardiovascular complications. SARS-CoV-2 and ACS pathogenesis SARS-CoV-2 infection exacerbates ACS through systemic inflammation, … Read more
Announcing a new publication for Acta Materia Medica journal. Neurologic disorders are the leading cause of illness and disability as a result of increased life expectancy and global population aging, highlighting the urgent need and great challenge for discovering neuroprotective agents with better efficacy and minimal side-effects. Catalpol, an iridoid glycoside derived from Rehmanniae Radix, … Read more
Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a new way to reduce obesity. Their study shows that supplying the gut with extra acetate reduces fat and liver mass in both normal and obese mice, as long as bacteria of the Bacteroides species is also … Read more
Treating migraine before the pain starts: New research shows ubrogepant eases premonitory symptoms, offering hope for millions seeking earlier and more effective relief. Study: Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial. Image Credit: GoodStudio / Shutterstock The most recent exploratory analysis from the phase 3 PRODROME … Read more
Announcing a new publication for Acta Materia Medica journal. The HIV-1 capsid protein (CA) plays a crucial role in viral replication by orchestrating nuclear entry through interactions with host nuclear pore complexes (NPCs). Recent research has revealed that HIV-1 CA actively disrupts NPC architecture via phenylalanine-glycine (FG)-repeat nucleoporin interactions, thereby enabling nuclear translocation of viral … Read more