Navigating the challenges and progress in dengue vaccine development

Dengue fever caused by a flavivirus named DENV is a major global health challenge, risking almost half of the world’s population. Since the early 20th century, the scientific community has faced multiple challenges to develop effective dengue vaccines. This spanned a variety of techniques – from the use of ox bile to weaken DENV to … Read more

Immune microRNAs drive new frontiers in cardiovascular disease research

  Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis. This review by Gareev et al. focuses on immune-derived microRNAs (immuno-miRs) as pivotal modulators of immune responses in cardiovascular settings, highlighting their roles in pathophysiology, diagnostic potential, and therapeutic promise. Introduction … Read more

Millions still lack access to basic eye care worldwide

Millions of people across the world still lack access to basic eye care such as glasses according to a new study led by Professor Rupert Bourne of Anglia Ruskin University (ARU). The research, published in The Lancet Global Health, measured the global availability and quality of treatment for uncorrected refractive error, one of the most … Read more

Global female infertility rates surge, hitting women in their late 30s hardest

A sweeping new analysis reveals that the burden of female infertility has soared over the past three decades, with age-standardized rates rising and women in their late 30s facing the highest risk worldwide. Study: Global, regional, and national burden of female infertility and trends from 1990 to 2021 with projections to 2050 based on the … Read more

New short film sheds light on the impact of climate change on brain health

A powerful new short film, from the FutureNeuro Research Ireland Centre and RCSI University of Medicine and Health Sciences sheds light on the urgent need to address the impact of climate change on brain health. Produced in collaboration with the International League Against Epilepsy (ILAE) Climate Change Commission, the film calls for urgent action to … Read more

City size reduces obesity and impulsivity through better lifestyle and education

New research reveals that larger cities see lower rates of both obesity and impulsivity, uncovering how lifestyle, education, and mental healthcare shape healthier urban populations. Study: Investigating the link between impulsivity and obesity through urban scaling laws. Image Credit: Markus Mainka / Shutterstock In a recent article published in the journal PLOS Complex Systems, researchers explored the … Read more

Most deadly drug-resistant infections in poorer countries go untreated, study shows

A massive treatment gap is leaving millions vulnerable to untreatable infections in low- and middle-income countries, as new data shows a dire shortfall in access to life-saving antibiotics. Study: Estimated undertreatment of carbapenem-resistant Gram-negative bacterial infections in eight low-income and middle-income countries: a modelling study. Image Credit: Shutterstock AI Generator / Shutterstock.com A recent Lancet Infectious … Read more

Midlife exercise may help lower Alzheimer’s risk

An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer’s disease, while inactivity may be detrimental to brain health. This is the main conclusion of a scientific paper published in Alzheimer’s & Dementia, which highlights the need to promote physical activity among middle-aged adults. The study is the result of a … Read more

Researchers develop drug cocktail to target enteroviruses

Enteroviruses are a group of viruses that cause everything from the common cold to meningitis, polio, type 1 diabetes, and much more. Over 100 different types have been described by researchers, and millions of people are infected each year. “Enteroviruses pose a significant global health problem,” said Erlend Ravlo, a PhD research fellow at the … Read more

Call for urgent support as US funding cuts threaten HIV/AIDS programs

Apr 9 2025 In the face of ongoing funding disruptions to US foreign assistance programmes, a group of international experts calls for urgent action to ensure the continuation of life-saving interventions and support for children and families affected by HIV/AIDS in sub-Saharan Africa. The new Health Policy analysis, published in The Lancet, estimates that 1 … Read more