Genomic screening uncovers hidden cancer and heart disease risk in young adults

A large Australian pilot shows that testing healthy young adults for high-risk genes can reveal serious disease risk years before symptoms appear, challenging traditional family history–based genetic testing. Study: Feasibility and outcomes of the DNA Screen nationwide adult genomic screening pilot. Image Credit: Westlight / Shutterstock In a recent study published in Nature Health, a … Read more

Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center. The research, published Dec. 31 in Cancer Discovery, demonstrates a practical method for simultaneously measuring specific DNA mutations and … Read more

Age-related sperm changes at imprint regions linked to autism risk

A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled “Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring.” The study – selected as our Editors’ Choice for January, 2026 – was led by first authors Eugenia Casella and Jana … Read more

Maternal exposure to metals rewires infants’ gut and resistance genes

New research reveals how trace metals mothers are exposed to during pregnancy can shape their babies’ gut bacteria, metabolic pathways, and even antibiotic resistance, potentially influencing lifelong health. Study: Prenatal exposure to trace elements impacts mother-infant gut microbiome, metabolome and resistome during the first year of life. Image Credit: Anusorn Nakdee / Shutterstock In a recent study … Read more

Genetic study reveals why some children respond better to myopia lenses

Myopia, or nearsightedness, has reached epidemic levels worldwide, particularly in East and Southeast Asia. Orthokeratology, which involves wearing specially designed contact lenses overnight to reshape the cornea, has proven effective in slowing axial eye growth—a key factor in myopia progression. Yet not all children benefit equally. Traditional predictors like age or initial degree of myopia … Read more

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer’s disease. At the heart of this condition lies the dysfunction of pancreatic islets, the mini-organs called organoids responsible for regulating blood sugar, in both autoimmune type 1 diabetes and stress-induced type 2 diabetes. … Read more

Early brain wiring holds clues to infant emotional development

In a comprehensive Genomic Press research article, scientists have uncovered remarkable insights into how the earliest brain connections shape infant emotional development, potentially offering new ways to identify children at risk for future behavioral and emotional challenges. The groundbreaking study, led by Dr. Yicheng Zhang and Dr. Mary L. Phillips at the University of Pittsburgh … Read more

Snowflake Acquires Crunchy Data: AI Expansion

Snowflake‘s strategic acquisition of Crunchy Data⁣ signals a major enhancement too its AI Data Cloud. ⁣This move‌ integrates Crunchy Data’s open-source‍ pgsql ‍ technology, also known as Postgres, directly into Snowflake’s platform, a notable⁢ upgrade for ‌AI development. The integration aims to empower users with faster, more efficient operations on the AI ⁢Data Cloud, addressing … Read more

How soy and gut microbes alter cancer treatment results

Groundbreaking research reveals how gut microbes and dietary soy can influence the outcome of cancer treatments, paving the way for a new frontier in personalized oncology. Study: Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Image Credit: CI Photos / Shutterstock In a recent study published in the journal Cell, researchers demonstrated that phytochemicals … Read more

Genome doubling identified as common event in metastatic cancer evolution

When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity. A new study from researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center (MSK) provides fresh insights about how cancers evolve when they metastasize – insights that could aid in developing strategies … Read more