Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis. This review by Gareev et al. focuses on immune-derived microRNAs (immuno-miRs) as pivotal modulators of immune responses in cardiovascular settings, highlighting their roles in pathophysiology, diagnostic potential, and therapeutic promise. Introduction … Read more
New research uncovers how heavy smoking rapidly disrupts blood and airway biology, revealing the hidden damage that accelerates disease risk in otherwise healthy adults. Study: The effects of heavy smoking on oxidative stress, inflammatory biomarkers, vascular dysfunction, and hematological indices. Image Credit: CGN089 / Shutterstock In a recent study in the journal Scientific Reports, researchers comprehensively evaluated … Read more
Researchers at Moffitt Cancer Center have found that tapping into the body’s own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy. Results of their study were published in the Journal for Immunotherapy of Cancer. TIL therapy … Read more
Immune Snapshot Could Revolutionize Cancer Care A groundbreaking study from UCL and the Francis Crick Institute has revealed a powerful connection between the immune system and cancer survival. Researchers have developed a novel tool called ImmuneLENS, which analyzes the proportion of T cells and B cells in a patient’s blood directly from their whole-genome sequencing … Read more
Introduction Neglected Tropical Diseases (NTDs) remain a significant health burden in tropical and subtropical regions, with limited treatment options and diagnostic capabilities. These diseases are often neglected in research and policy, yet they contribute to high mortality and morbidity worldwide. Nanotechnology, particularly the conjugation of nanomaterials with drugs, presents an innovative approach to improving both … Read more
The immune systems of cancer patients are highly disrupted, with those who have a higher number of immune cells in their blood having a better survival rate, finds a new study that uses a pioneering technique developed by researchers at UCL and the Francis Crick Institute. The tool, described in Nature Genetics, is called Immune … Read more
Researchers have developed a new method to grow T cells that have greater longevity and can more efficiently destroy cancer cells in mouse models of melanoma compared to those grown in traditional growth media Study: Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy. Image Credit: ART-ur/Shutterstock.com … Read more