Humanized liver organoids double survival rate in rodent models

One reason why our livers excel at clearing waste from our blood system is that the organ functions according to three key “zones” that perform specific major tasks. So, if scientists hope to create self-growing patches of liver organoid tissue that could help repair damaged organs, it’s important that the lab-grown tissue faithfully reproduce such … Read more

Study explores how Adapted Argentine tango dance therapy can help breast cancer survivors

Adapted Argentine tango dance therapy is helping some breast cancer survivors regain natural balance and sensation after experiencing neuropathy, a common side effect of chemotherapy treatment. Expansion of a new clinical study will look further at how this musical movement intervention can “rewire” the brain to improve function after chemotherapy-related nerve changes.  Lise Worthen-Chaudhari, PhD … Read more

Prolonging pain relief in surgery with dexmedetomidine and spinal anesthesia

Heitor Medeiros, MD, and A. Sassan Sabouri, MD, of the Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital, are the lead and corresponding authors, respectively, of a paper published in the British Journal of Anaesthesia (BJA).  How would you summarize your study?  Spinal anesthesia is widely used to numb patients during … Read more

Early menopause linked to worse cognitive function in later life

A team of researchers from the Tohoku University Graduate School of Medicine and Tokyo Metropolitan Institute of Medical Science found that women who entered menopause before the age of 40 had worse cognitive outcomes than women who entered menopause after the age of 50. This finding may be useful for clinicians, when assessing their patient’s … Read more

Equipping Clinicians to Navigate Social Determinants of Health

Mindy Hoang, MD Credit: Linkedin Some of the largest determinants of health are social and include factors like housing, food access, income, and immigration status. These factors limit the benefits that medical treatment can offer, especially in under-resourced settings, proving a frustration for many clinicians. Clinicians at Wayne State University in Detroit recognized that understanding … Read more

Music therapy intervention improves mental health for heart failure and COPD patients

A new study from University Hospitals Connor Whole Health found that it was feasible to conduct a hybrid music therapy intervention for patients with heart failure and patients with chronic obstructive pulmonary disease (COPD). Participants reported positive effects on their mental health, and the pilot uncovered solutions to improve future research with this population. The … Read more

Early combination treatment can prevent heart attacks and save lives

Patients who receive an add-on medication soon after a heart attack have a significantly better prognosis than those who receive it later, or not all. This is according to a new study from researchers at Lund University in Sweden and Imperial College London. The findings suggest that treating patients earlier with a combination of statins … Read more

Gut bacteria turn bile acids into allies against cancer

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators. The study was published on April 15 in Cell. “I was very surprised by our findings. … Read more

New study examines how obesity alters brain’s reward circuits

Obesity is on the rise. Among U.S. adults aged 20 or older, 4 in 10 met the criteria for obesity in the most recent National Health and Nutrition Examination Survey, up from roughly 3 in 10 two decades earlier. People with obesity have a significantly greater risk of developing Type 2 diabetes. Despite recent health … Read more

New analysis clarified the link between “exclusive” use of e-cigarettes and COPD

A Johns Hopkins Medicine-led analysis of medical information gathered on a diverse group of almost 250,000 people over four years has significantly clarified the link between the “exclusive” use of e-cigarettes and chronic obstructive pulmonary disease (COPD), as well as high blood pressure in a sub-group of adults 30 to 70 years of age. The … Read more