A long-running debate in vaccine design revolves around whether a vaccine should be optimized to prevent the virus from replicating inside an infected host or prevent the virus from transmitting to others. New research led by Penn State scientists suggests there may not have to be a tradeoff. The study in animal models, published today … Read more
First published in 2010, the EULAR recommendations for the management of RA, the most frequent inflammatory rheumatic disease, have been relied upon by healthcare professionals and organisations worldwide to offer an up-to-date and robust analysis of the effectiveness and practical use of available DMARDs – from conventional agents such as methotrexate to biologics and Janus … Read more
Cells behave like cities and organelles carry out infrastructural roles: Mitochondria are powerhouses, the endoplasmic reticulum serves as a transport hub and lysosomes help with waste disposal. Communication between different parts of a cell is important for metabolism. This inter-organelle communication can occur at sites where these parts are in contact with each other, known … Read more
A smartphone app designed to tackle the underlying psychological causes of premature ejaculation can significantly improve sex life and delay ejaculation, while offering a way to reduce stigma around the condition, say researchers. Data from the CLIMACS study are presented today [Saturday 14 March 2026] at the European Association of Urology Annual Congress (EAU26) in … Read more
A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This was discovered by researchers at the Rudolf Virchow Centre at the University of Würzburg. The human body cannot produce vitamin B2 – also known as riboflavin – itself; it must absorb the important substance through diet. The … Read more
Researchers recommended a tailored, scientifically validated exercise program to individuals receiving chemotherapy for cancer, and those who were on a two-week chemotherapy schedule and followed the exercise prescription were able to maintain their walking-step goals, use resistance bands, and stay mentally sharper compared to patients who did not exercise. Led by Karen Mustian, PhD, MPH, … Read more
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found that excessive smartphone use is closely associated with disordered eating, including uncontrolled eating and emotional overeating, as well greater symptoms of food addiction in young people with no diagnosis of an eating disorder. The research, published in the Journal of Medical Internet Research, established a significant and consistent association between Problematic Smartphone Use … Read more
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence shows that CD4+ T cells are far more than immune “helpers.” Within tumors, CD4+ T cell subsets exhibit remarkable heterogeneity, ranging from cytotoxic CD4+ CTLs to immunosuppressive regulatory … Read more
A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer and HIV, addressing a major limitation of current treatments. Their findings, published today in Science Advances, describe a manufacturing approach that, compared … Read more
A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing nerve damage in conditions such as cerebral paralysis and multiple sclerosis (MS). The finding, publishing March 13 in the Cell Press journal Neuron, reveals a naturally existing pathway that promotes regeneration after nerve damage and could open new doors for treating diseases like MS by leveraging molecules that are already present in the human body. … Read more