compound

Single dose of novel drug shows tumor-clearing potential in breast cancer models

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Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots. Now, researchers reporting in ACS Central Science have created a novel treatment that eliminated small breast tumors and significantly … Read more

Could camembert cheese hold the key to better memory?

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Myristamide, a fatty acid amide found in Camembert cheese, enhances cognitive function and brain-derived neurotrophic factor (BDNF) levels, offering potential insights into combating cognitive decline. Study: Fatty acid amides present in Camembert cheese improved cognitive decline after oral administration in mice. Image Credit: melei5/Shutterstock.com In a recent article in Neuroscience Research, researchers examined how Camembert cheese and … Read more

Insilico Medicine nominates ISM1745 as preclinical candidate for MTAP-deleted cancers.

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Insilico Medicine Advances AI-Powered Drug Discovery with Promising New Candidate for MTAP-Deleted Cancers Insilico Medicine (‘Insilico’), a leading clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, has announced a significant milestone. The company has nominated ISM1745, a novel MTA cooperative PRMT5 inhibitor, as a preclinical candidate (PCC) for the treatment of MTAP-deleted cancers. … Read more

Shiitake-based supplement may help prevent liver damage progression

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Early use of AHCC during hepatitis stages shows potential to reduce the risk of cirrhosis, according to new research Study: AHCC inhibited hepatic stellate cells activation by regulation of cytoglobin induction via TLR2-SAPK/JNK pathway and collagen production via TLR4-NF-κβ pathway. Image Credit: guys_who_shoot/Shutterstock.com A recent report in Gastrointestinal and Liver Physiology presents the effect of … Read more