Senolytics offer hope for more precise Alzheimer’s treatments

A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled “Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease.” In this study, a research team from Dalhousie University, led by Sultan Darvesh, discovered that certain anti-aging compounds, known as senolytics, can block … Read more

Breakthrough in cannabidiol formulation improves treatment for epilepsy and MS

Scientists at the University of South Australia have come up with an innovative solution to improve the effectiveness of cannabidiol to treat epilepsy, multiple sclerosis and other neurodegenerative diseases. Cannabidiol (CBD) is a non-psychoactive compound found in the cannabis plant. It is widely prescribed for its analgesic, anti-inflammatory and neuroprotective properties, but its clinical applications … Read more

Enhancing Bedaquiline with Curcumin for Effective M. abscessus Treatment

Archyde Curcumin and Bedaquiline: A Novel Combination Therapy Against Drug-Resistant Infections Table of Contents 1. Curcumin and Bedaquiline: A Novel Combination Therapy Against Drug-Resistant Infections 2. Fighting Back Against Antibiotic Resistance: A New Hope? 3. the Power of Synergy: Curcumin and Bedaquiline 4. Real-World Implications and Future Directions 5. Addressing Potential Counterarguments 6. Looking Ahead: … Read more

Adding curcumin boosts the efficacy of bedaquiline in combating M. abscessus infections

Mycobacterium abscessus is a fast-growing, pathogenic mycobacteria that can cause lung infections, and people who have respiratory conditions or are immunocompromised face a higher risk. It can also cause skin infections. The microbe is closely related to the one that causes tuberculosis and is naturally resistant to many antibiotics. Infections often require a year or … Read more

NIH researchers define topical steroid withdrawal diagnostic criteria

Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in the body. Scientists from NIH’s National Institute of Allergy and Infectious Diseases (NIAID) identified treatments that could be studied in clinical … Read more

Impact of excessive alcohol consumption on digestive health

Excessive alcohol consumption is a significant public health concern, responsible for approximately 6% of all deaths and contributing to 5.1% of the global disease burden. Alcohol use is a major risk factor for over 200 diseases, including liver cirrhosis, pancreatitis, and esophageal cancer, with a particularly high incidence of gastrointestinal diseases. More than 50% of … Read more

Cordycepin helps tired mice run longer and think better, study finds

Could a natural fungus compound fight fatigue and sharpen your mind? New research suggests cordycepin might hold the key to boosting endurance and protecting brain function when pushed to the limit. Cordyceps parasitic fungus growing on an ant, also known as zombie-ant fungus, 3D illustration. Study: Cordycepin combined with antioxidant effects improves fatigue caused by excessive … Read more

Study reveals ferulic acid’s potential in preventing colon cancer

Colon cancer continues to be one of the leading causes of cancer-related deaths worldwide, with poor dietary habits identified as a major risk factor. Ferulic acid, a phenolic compound abundant in many plant foods, has previously demonstrated potential anti-cancer properties by inhibiting cell proliferation and promoting apoptosis. Despite its promising effects, the impact of ferulic … Read more

AI-based technology accelerates discovery of new tuberculosis drug candidates

Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and into the lungs, the pathogen that causes “TB” can lead to chronic cough, chest pains, fatigue, fever and weight loss. While infections are more extensive in other parts of the world, a serious tuberculosis … Read more

Microbial compound offers hope for vitiligo treatment

A natural compound derived from gut-friendly bacteria significantly slows the progression of vitiligo and may restore pigmentation, reports a new Northwestern University pre-clinical study in mice. The findings could offer hope to millions affected by the autoimmune disease, which causes visible patches of skin discoloration and carries profound emotional and physical consequences. The results in … Read more