Bottom Line: A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient’s risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, with high accuracy. Journal in Which the Study was Published: Cancer Discovery, a journal of the American Association for Cancer Research … Read more
32 Scientists have observed that reducing dietary protein can slow the progression of liver tumours in mice whose livers are unable to efficiently remove ammonia. The results suggest that a normal dietary component may become a driver of cancer growth when liver function is impaired, as per the study published in Science Advances. Ammonia accumulation … Read more
Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free DNA (cfDNA) fragmentation patterns and repeat landscapes can detect early liver fibrosis and cirrhosis, and may also reveal signals of broader chronic disease burden. The research was supported in part by the National Institutes of Health, and … Read more
Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score that predicts the risk of liver cancer. Published in the scientific journal Proceedings of the National Academy of Sciences, the study establishes that the protein MYCN drives liver tumorigenesis, specifically of the type of tumors found … Read more
Immunotherapy – which activates the body’s own immune system to kill cancer cells – has not worked well against a rare and fatal liver cancer, but a new Cornell University study finds an existing FDA-approved drug may allow the immunotherapy to fight the cancer as intended, opening the door to a potential treatment. Fibrolamellar carcinoma … Read more
A recent study suggests reducing dietary protein may slow liver cancer development in people with impaired liver function, but healthy individuals likely do not need to worry. New research indicates that lowering protein intake could reduce the risk of liver cancer or slow its progression in individuals with liver disease. Scientists from Rutgers University highlight … Read more
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not. In a study published in the January 27 online issue of Nature Medicine (DOI 10.1038/s41591-025-04177-6), the researchers found that antibody-producing immune cells called IgG1 plasma … Read more
Long-term national data reveal that even modest reductions in alcohol consumption across the whole population could prevent thousands of cancer deaths, especially among older Australians. Study: Alcohol consumption and mortality from four alcohol-related cancers in Australia 1950-2018: a time series analysis. Image credit: metodej/Shutterstock.com Population-level reduction of alcohol consumption in Australia could, over the long … Read more
The liver plays a vital role in several key bodily functions, including metabolism, detoxification, and digestion. Due to its rich blood supply and complex structure, it is also susceptible to abnormal growths, some of which may be benign while others can be malignant. Also read | Doctors warn: Liver cancer could hit you in your … Read more
Researchers discover that inflammation and aging contribute to non-viral liver cancer development. Green tea’s role in reversing some of the pathway dysregulation that may contribute to the cancer development and other therapies explored. Liver cancer can arise spontaneously from healthy liver tissue. Recently, however, researchers have discovered an increasing correlation between some liver cancers and … Read more