Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.  In the study, published Jan. 8 in the journal Nature … Read more

Tiny vesicles offer powerful new approach for cancer treatment

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania. The experimental approach, which uses tiny capsules called small extracellular vesicles (sEVs), could offer an innovative new type of immunotherapy treatment and is poised … Read more

Air pollution before conception may increase child BMI

In a study of more than 5,000 mothers and their children, exposure to air pollution during the three months before pregnancy predicted higher child body mass index (BMI) and related obesity risk factors up to two years of age. Findings from the study, which was supported by the National Institute of Environmental Health Sciences, were … Read more

The Christie launches unique training program for cancer care doctors

A unique training programme for a new breed of cancer care doctors is underway at The Christie in Manchester, an international center of excellence in cancer care. Dr Richard Berman (left) welcomes Dr Ahmed Aboelnaga to The Christie as the first supportive oncology fellow. Image Credit: The Christie NHS Foundation Trust Three supportive oncology fellows have … Read more

McMaster researchers identify key immune cells linked to severe asthma

Researchers at McMaster University have made an important discovery in the field of asthma research, identifying a new population of immune cells that may play a crucial role in the severity of asthma symptoms.  The study, published in Science Translational Medicine on Jan. 15, 2025, sheds light on the complex mechanisms behind severe asthma and … Read more

New target identified for potential colorectal cancer treatment

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system. It typically starts as abnormal growths called polyps that form in the lining of the colon or rectum. Over time, some of these polyps can become cancerous if left untreated. CRC … Read more

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB …

A clinical trial published in the New England Journal of Medicine showed that the oral antibiotic levofloxacin taken once-daily for six months substantially reduced the risk of developing drug-resistant tuberculosis (TB), and almost halved adults’ and children’s risk of developing multidrug-resistant TB. “Multidrug-resistant TB is a major global public health problem, affecting over 400,000 people … Read more

New AI model offers hope for detecting brain cancer spread without surgery Researchers Have Developed A…

Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients’ cancer without aggressive surgery. The proof-of-concept study, co-led by McGill University researchers Dr. Matthew Dankner and Dr. Reza Forghani, alongside an international team of clinicians and scientists, demonstrated the AI model can detect … Read more

New model analyzes CT scans to identify high-risk individuals

Researchers at Case Western Reserve University, University Hospitals and Houston Methodist will harness the power of artificial intelligence (AI) to more accurately predict risk of heart failure and other cardiovascular events, including estimating when an adverse event might occur, by developing an AI model that “learns” from patient scans. Cardiovascular disease is the leading cause … Read more

The impact of fall-risk medications on injuries in COPD patients

People with COPD experience more falls and related injuries requiring medical care when using common fall-risk increasing drugs, according to a new study. The study is published in the November 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal.  Chronic obstructive pulmonary disease (COPD) is an inflammatory lung … Read more