Sclerosis

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

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Emerging evidence suggests widely used metabolic drugs could influence brain aging pathways, yet large clinical trials are still needed to confirm whether they truly alter the course of neurodegenerative disease. Study: The promise of GLP-1 receptor agonists for neurodegenerative diseases. Image Credit: Antonio Marca / Shutterstock In a recent review published in the Journal of Clinical … Read more

EBV-linked killer T cells implicated in multiple sclerosis

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Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million Americans.  The study, published Feb. 5 in Nature Immunology, found that certain types of CD8+ “killer” T cells – immune cells that destroy damaged or infected cells … Read more

Brain cell precursors show constant myelin-making drive

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In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells – one of the few brain cell types that continue to be produced in the adult brain – undergo differentiation widely and at a constant pace, rather than “as needed” in response to injury or advancing age. The findings, … Read more

Long-term air pollution exposure raises motor neuron disease risk

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Even at relatively low pollution levels, chronic exposure to fine particles and nitrogen dioxide was linked to higher disease risk, faster functional decline, and greater need for invasive ventilation in people with motor neuron disease. Study: Long-Term Exposure to Air Pollution and Risk and Prognosis of Motor Neuron Disease. Image Credit: Kateryna Kon / Shutterstock … Read more

Protect Mitochondria: Stress Damage Breakthrough

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BREAKING: New Hope for Treating Mitochondrial Damage Table of Contents BREAKING: New Hope for Treating Mitochondrial Damage What We Know So Far targeting Mitochondrial Fission Uncovering a Vulnerable… The post Protect Mitochondria: Stress Damage Breakthrough appeared first on NewsyList. Source link

New short film sheds light on the impact of climate change on brain health

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A powerful new short film, from the FutureNeuro Research Ireland Centre and RCSI University of Medicine and Health Sciences sheds light on the urgent need to address the impact of climate change on brain health. Produced in collaboration with the International League Against Epilepsy (ILAE) Climate Change Commission, the film calls for urgent action to … Read more

TDP-43 dysfunction in brain blood vessels may drive Alzheimer’s and ALS progression

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Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer’s, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain’s blood vessels. University of Connecticut researchers report in the April 16 issue of Science Advances that mutations in the TARDBP gene that reduce TDP-43 protein levels also impair the cells … Read more

Annual COVID-19 boosters crucial for immunocompromised individuals

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New research findings provide solid evidence that annual COVID-19 vaccine booster doses continue to be advisable for certain immunocompromised people, researchers at McGill University say. The researchers looked at how often people with immune-mediated inflammatory diseases (IMIDs) got COVID-19 despite having received at least three doses of an mRNA COVID-19 vaccine. IMIDs – including rheumatoid … Read more

Study identifies brain areas crucial for word memory in epilepsy

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The parts of the brain that are needed to remember words, and how these are affected by a common form of epilepsy, have been identified by a team of neurologists and neurosurgeons at UCL. The new study, published in Brain Communications, found that shrinkage in the front and side of the brain (prefrontal, temporal and … Read more

Breakthrough in cannabidiol formulation improves treatment for epilepsy and MS

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Scientists at the University of South Australia have come up with an innovative solution to improve the effectiveness of cannabidiol to treat epilepsy, multiple sclerosis and other neurodegenerative diseases. Cannabidiol (CBD) is a non-psychoactive compound found in the cannabis plant. It is widely prescribed for its analgesic, anti-inflammatory and neuroprotective properties, but its clinical applications … Read more