Gene

Study reveals TCM-Based strategies for ferroptosis modulation

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Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries. The powerful bioactive compounds in … Read more

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

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A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future … Read more

Platelet-rich plasma may enhance ovarian rejuvenation and improve egg quality in women

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A new research paper was published in Aging (Aging-US) on February 18, 2025, Volume 17, Issue 2, titled “Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP).” Researchers from IVIRMA New Jersey, Yale School of Medicine, Yale University, and Acibadem Mehmet Ali Aydinlar University studied how a treatment called platelet-rich … Read more

Study reveals how air pollution contributes to Alzheimer’s disease

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Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs. Breathing in wildfire smoke or automobile-related city smog doesn’t just increase the risk of asthma and heart disease-it may also contribute to brain diseases as diverse as Alzheimer’s and autism. Scientists at Scripps Research have discovered … Read more

Cambridge launches program to tackle engineered pandemic risks

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Covid-19 showed us how vulnerable the world is to pandemics – but what if the next pandemic were somehow engineered? How would the world respond – and could we stop it happening in the first place? These are some of the questions being addressed by a new initiative launched today at the University of Cambridge, … Read more

Advancements in molecular diagnostics for hematopoietic and lymphocytic neoplasms

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Hematopoietic and lymphocytic neoplasms (HLNs) are a diverse group of malignancies affecting blood and lymphatic systems, with outcomes varying from manageable conditions to fatal diseases. Traditional classifications rely on morphology, karyotyping, and fluorescence in situ hybridization (FISH). However, recent advancements in next-generation sequencing (NGS) allow simultaneous genetic profiling of multiple genes, enhancing diagnostic precision and … Read more

New brain map reveals insights into multiple sclerosis development

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NIH study reveals key players underlying disease onset and repair. Using an animal model of multiple sclerosis (MS), researchers at the National Institutes of Health (NIH) have created a four-dimensional brain map that reveals how lesions similar to those seen in human MS form. These findings, published in Science, provide a window into the early … Read more

Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

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Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA). However, the cell heterogeneity of chondrocytes in human articular cartilage is still not well defined, which hinders understanding of the pathogenesis of OA. This research, published in the Genes … Read more

Can coffee push back Parkinson’s? New study uncovers key genetic link

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New research suggests your daily coffee habit might help delay the onset of Parkinson’s disease—but don’t count on it to lower your risk or slow its progression. Study: Coffee consumption is associated with later age-at-onset of Parkinson’s disease. Image Credit: Kittyfly / Shutterstock *Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should … Read more

Discovery of new bat flu strain with potential to infect other species

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A newly identified bat influenza virus, H18N12, carries mutations that may enhance its ability to jump between species, underscoring the need for vigilant surveillance to prevent future outbreaks. Study: Genomics of novel influenza A virus (H18N12) in bats, Caribe Colombia. Image Credit: Shutterstock AI Generator / Shutterstock.com In a recent study published in Scientific Reports, scientists … Read more