Schizophrenia affects millions worldwide, yet its causes remain one of the greatest medical mysteries. In an exclusive Genomic Press Interview, Dr. Consuelo Walss-Bass, a pioneering researcher in psychiatric genetics, shares how both genetic predisposition and environmental factors contribute to severe mental health disorders. As the John S. Dunn Foundation Distinguished Chair in Psychiatry at UTHealth … Read more
A new review was published in Oncotarget, Volume 16, on March 13, 2025, titled “Signaling pathway dysregulation in breast cancer.” In this review article, Dinara Ryspayeva and colleagues from Brown University provide a detailed look at how breast cancer cells change the way they communicate and grow-helping tumors survive, spread, and resist treatment. The review … Read more
A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominate strain. University of Pittsburgh School of Medicine scientists made the discovery when combing through local hospital data – and then confirmed that … Read more
A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S. The report comes from the laboratory of Stephanie Schmit, PhD, MPH, and was published in JAMA Network Open. It serves as an opportunity to better understand how … Read more
A research led by Sergio P. Acebrón, Researcher Ikerbasque at the UPV/EHU, develops a key tool to visualize the immune response to abnormal DNA, opening new avenues for the treatment of diseases. The study, published in the prestigious journal EMBO Journal, reveals why some tumors escape the immune system, and offers a method to visualize … Read more
A groundbreaking peer-reviewed Thought Leaders Invited Review article in Brain Medicine (Genomic Press, New York) explores how CD2-associated protein (CD2AP) contributes to Alzheimer’s disease (AD), one of the most devastating neurodegenerative disorders affecting millions worldwide. CD2AP, initially identified for its role in cellular transport and cytoskeletal architecture, has now emerged as a crucial factor in … Read more
A new research paper was published in Aging (Aging-US) on February 25, 2025, Volume 17, Issue 2, titled “Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study.” Researchers from multiple institutions, led by first author and corresponding author Deidra R. Fricke from the University of Pittsburgh, studied the genetic and lifestyle factors that influence … Read more
An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black women have nearly identical mutations to other previously studied populations. But researchers also found a few notable differences that may be clinically relevant. Our analysis shows the importance of researching … Read more
Researchers studying a protein linked to a rare, severe disease have made a discovery that sheds light on how cells meet their energy needs during a severe metabolic crisis. The findings could lead to new treatments for the disease and open new avenues of research for other conditions involving impaired fat metabolism. When scientists at … Read more
TANGO2 Deficiency Disorder: Unraveling the Mystery of Cellular Energy Crisis A Groundbreaking Discovery at the Centre for Genomic Regulation A recent study conducted by researchers at the Centre… The post New Insights into TANGO2: Shedding Light on Fat Metabolism in Severe Metabolic Crises Explore how TANGO2 deficiency impacts energy production and potential treatment strategies through … Read more