major depressive disorder

How could bisphenol A raise depression risk? Study identifies six key molecular targets

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Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may influence biological pathways tied to major depressive disorder. Study: Bisphenol a exposure and major depressive disorder: an integrative analysis combining network toxicology, molecular docking, genetic epidemiology, and transcriptomic validation. Image Credit: monticello / Shutterstock A new study … Read more

New review calls for biologically grounded approach to psychiatric diagnosis

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A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling. The review, authored … Read more

Short-duration psychedelic therapy shows promise for major depression treatment

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A controlled clinical trial suggests a fast-acting psychedelic approach may reduce depressive symptoms, but researchers stress careful interpretation and the need for larger long-term studies. Study: A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial. Image Credit: BLACKDAY / Shutterstock In a recent study published in the journal Nature Medicine, researchers … Read more

Improving survival in people with severe psychiatric disorders

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An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap faced by people with serious mental illnesses by tackling cardiovascular risk and metabolic disease head-on. Editorial: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have potential to transform health outcomes for persons with bipolar disorder, schizophrenia, major depressive disorder … Read more

VNS shows durable benefits in Treatment-Resistant depression

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Two-year data show that adding VNS to standard care can produce lasting symptom, function, and quality-of-life benefits in one of the most difficult-to-treat depression populations. Study: Durability of the benefit of vagus nerve stimulation in markedly treatment-resistant major depression: a RECOVER trial report. Image credit: BigBlueStudio/Shutterstock.com In a recent study published in the International Journal … Read more

Study links cannabis addiction to mental health disorders

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New research uncovers how cannabis addiction, not casual use, is genetically tied to severe mental health conditions, raising red flags for policy, treatment, and prevention. Study: The genetic relationship between cannabis use disorder, cannabis use and psychiatric disorders. Image credit: PeopleImages.com – Yuri A/Shutterstock.com In a recent study published in the journal Nature Mental Health, researchers in … Read more

Multiple chatbots simulate group therapy to help women manage premenstrual syndrome

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A research team has designed and implemented a group motivational interviewing system using multiple chatbots to support premenstrual syndrome (PMS), a common disorder among women. The system consists of chatbots serving as a facilitator or peers, which simulate a group counseling environment for PMS management. The study could provide valuable insights into the use of … Read more

Eye Exams Crucial for Mental Health: New Study

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Mental Health, Retinal Disease Linked: Study Shows Higher Risk Table of Contents Mental Health, Retinal Disease Linked: Study Shows Higher Risk mental health link: bipolar, depression tied to higher risk of retinal disease, vision loss the connection between mental health and vision key findings at a glance did you know? study methodology the numbers behind … Read more

Study Underscores Need for Eye Exam in Psych Disorders

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TOPLINE: Individuals older than 50 years with bipolar or major depressive disorder were more likely to have retinal disease, and those with a diagnosis of retinal disease and a psychiatric illness were at sharply higher risk for impaired vision than those with retinal disease alone. METHODOLOGY: Researchers conducted a retrospective cohort analysis of adults aged … Read more

More than a mood disorder: Study reveals depression ages brain faster than normal | Health

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Brain ageing is related to cognitive decline, which in turn diminishes essential cognitive functions like memory, critical thinking, and more. Brain ageing is also associated with neurodegenerative conditions like dementia and Alzheimer’s. The scientific community is continuously trying to identify risk factors. Depression alters brain structure.(Shutterstock) A study published in the journal Psychological Medicine has … Read more