New discovery reveals immune molecule’s role in Alzheimer’s disease

A new way of thinking about Alzheimer’s disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer’s and other neurodegenerative diseases. University of Virginia School of Medicine scientists have been investigating the possibility that Alzheimer’s is caused, at least in part, by the immune system’s wayward attempts … Read more

High fat diet disrupts metabolism and increases disease risk

Consuming a high-fat diet can lead to a variety of health problems – not only weight gain but also an increased risk of diabetes and other chronic diseases. At the cellular level, hundreds of changes take place in response to a high-fat diet. MIT researchers have now mapped out some of those changes, with a … Read more

Protect Mitochondria: Stress Damage Breakthrough

BREAKING: New Hope for Treating Mitochondrial Damage Table of Contents BREAKING: New Hope for Treating Mitochondrial Damage What We Know So Far targeting Mitochondrial Fission Uncovering a Vulnerable… The post Protect Mitochondria: Stress Damage Breakthrough appeared first on NewsyList. Source link

Tufts researchers develop dental floss sensor for real time stress monitoring

Chronic stress can lead to increased blood pressure and cardiovascular disease, decreased immune function, depression, and anxiety. Unfortunately, the tools we use to monitor stress are often imprecise or expensive, relying on self-reporting questionnaires and psychiatric evaluations.  Now a Tufts interdisciplinary engineer and his team have devised a simple device using specially designed floss that … Read more

Discovery reveals how neuronal ion channels store molecular memory

Researchers have discovered how an ion channel in the brain’s neurons has a kind of ‘molecular memory’, which contributes to the formation and preservation of lifelong memories. The researchers have identified a specific part of the ion channel at which new drugs for certain genetic diseases could be targeted. The study, led from Linköping University … Read more

Macrophages take center stage in liver healing after injury

The liver is famous for its remarkable ability to regenerate, but that healing power depends heavily on the actions of its resident immune cells. A new study spotlights macrophages, the liver’s cleanup and repair specialists, revealing that these cells quickly adapt after injury to clear debris and support tissue recovery. Researchers from the National Institutes … Read more

Study identifies a new key factor contributing to aggressive nature of pancreatic cancer

Pancreatic cancer is one of the most aggressive cancers and has one of the lowest survival rates-only 10% after five years. One of the factors contributing to its aggressiveness is its tumor microenvironment, known as the stroma, which makes up the majority of the tumor mass and consists of a network of proteins and different … Read more

Study reveals brain circuit behind apathy in advanced cancer

The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss. But new research from Washington University School of Medicine in St. Louis challenges that long-held assumption, showing instead that these behavioral changes stem … Read more

Unlocking the power of MDA5 protein modifications in antiviral defense

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.  The PNAS publication explains how two protein modifications activate MDA5, an essential immune protein, to sense invaders, limit viral replication and fight infections. This process is key … Read more

New insights into how myasthenia gravis antibodies disrupt muscle function

People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles we use to blink, smile or even move our body around. Researchers have known that the disease is caused by miscommunication between nerves and muscles. The body’s immune system mistakenly produces “autoantibodies,” or antibodies that attack … Read more