TOPLINE: Continuing metformin throughout the first trimester in women with polycystic ovary syndrome (PCOS) showed the potential to reduce miscarriage risk (odds ratio [OR], 0.64) and increase clinical pregnancy rates (OR, 1.57) compared with placebo. A meta-analysis of 12 randomized controlled trials involving 1708 women suggested that stopping metformin at pregnancy confirmation might be less … Read more
With the explosive popularity of glucagon-like peptide 1 (GLP-1) agonists, physicians say a key avenue in treating obesity is being underutilized by many clinicians: First-generation anti-obesity medications (AOMs). “First-generation medications don’t get as much attention as the newer ones,” said Courtney Younglove, MD, an obesity specialist and founder of Heartland Weight Loss in Overland Park, … Read more
A new scientific review uncovers how gut microbes passed from mother to child may hold the key to obesity’s genetic puzzle, offering fresh hope for more effective prevention strategies. Impact of the gut microbiota on BMI via hypothalamic control of appetite and metabolism, and mechanisms that underlie the transgenerational effects of the gut microbiota on … Read more
New research links maternal PCOS and testosterone to reduced weekend activity in boys and weaker grip strength in girls, highlighting the lasting impact of in-utero hormone exposure on children’s physical development. Image Credit: Marta Design / Shutterstock Boys born to mothers who have polycystic ovary syndrome (PCOS) or who have higher levels of testosterone during the third … Read more
Polycystic ovary syndrome (PCOS) represents a significant health concern for women of reproductive age, manifesting as a complex endocrine disorder with diverse clinical presentations. Characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, PCOS affects 5% to 20% of women and stands as a leading cause of anovulatory infertility. The pathophysiology of PCOS involves abnormal … Read more
Study highlights how PCOS alters uterine lining | Image Credit: © Pakorn – © Pakorn – stock.adobe.com. Differences in uterine lining composition The composition of cells and gene expression in uterine lining differ between women with polycystic ovary syndrome (PCOS) vs those without PCOS, according to a recent study published in Nature Medicine.1 Investigators developed … Read more
Having one or more common gynecological disorders, such as endometriosis or heavy or irregular periods, may be linked to a heightened risk of heart disease and conditions that affect blood flow to the brain (cerebrovascular disease), finds a pooled data analysis of the available evidence published online in the journal Heart. Although the quality of the … Read more
HERE are the five key signs of a “common condition” that can be life-altering & when you should get checked. The HSE issued an alert over Polycystic Ovary Syndrome. PCOS is a hormonal disorder that affects women’s ovaries, often during their reproductive years. It is characterised by a combination of symptoms, including irregular or absent … Read more
Preliminary study: identifying women with PCOS using ICD-10 code E28.2 in the French National Health Data System The French National Health Data System “Système National des données de Santé” (SNDS) is a national database that contains a wide range of health-related information. SNDS database covers nearly the entire French population (98.8%), which accounted for more … Read more