The natural environment recreated “A key challenge with organoids is the balance between cell growth and… The post Liver Organoids: Dresden Model for Regeneration appeared first on Archynetys. Source link
Critical Path Institute® (C-Path) applauds the publication of a new study in the Journal of Neurology that offers critical longitudinal insights into how symptoms and functional impacts evolve for individuals with early Parkinson’s disease (PD). Led by Jamie Adams, M.D., and Jennifer Mammen, Ph.D., long-time partners of C-Path’s Critical Path for Parkinson’s consortium, the paper is titled, “Three … Read more
Learning French, reading the latest Andy Weir novel, hanging out with friends for St. Patrick’s Day – language is central to all these everyday activities. Seemingly effortless from childhood, language, it turns out, is quite complex, not constrained to one set of genes or one region in the brain. Cognitive neuroscientists are now using a … Read more
An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common epilepsies, assembling evidence from genome-wide association studies, whole-exome sequencing projects, and advanced statistical modeling to illuminate the polygenic architecture that underpins these heterogeneous neurological disorders. The synthesis, led by Dr. Olav B. Smeland of the Centre for … Read more
A species of gut bacteria called Roseburia inulinivorans is specifically associated with human muscle strength and improved muscular performance in mice, finds research published online in the journal Gut. R inulinivorans changes certain metabolic processes in muscle, and converts muscle fibres to ‘fast-twitch (type II)—designed for short intensive movement, such as sprinting and weights-the findings show. R inulinivorans holds promise … Read more
A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling. The review, authored … Read more
A new study led by researchers at The University of Texas MD Anderson Cancer Center found that prostate cancer patients with low testosterone levels may have a higher risk of cancer progressing to a more aggressive form while under active surveillance. The findings, published in the The Journal of Urology, suggest that baseline testosterone may serve as a useful clinical marker to better stratify risk and tailor monitoring strategies for patients choosing active surveillance. Active surveillance is a safe and effective option for many men with early-stage prostate cancer. However, identifying which patients … Read more
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that depleting a clotting protein made by the liver could slow down pancreatic cancer. The research, recently published in Gastroenterology and led by Melissa L. Fishel, PhD, shows that reducing fibrinogen in mouse models shrinks primary pancreatic ductal adenocarcinoma (PDAC) tumors and reduces their ability to … Read more
A recent study published in Engineering has shed light on a novel therapeutic target for improving anti-angiogenic treatment in colorectal cancer (CRC). The research, conducted by an international team of scientists from institutions including Sun Yat-sen University and The Chinese University of Hong Kong, identified the RNA N⁶-methyladenosine (m⁶A) reader insulin-like growth factor 2 mRNA-binding … Read more
A new perspective argues that understanding the lifelong web of environmental exposures, from early childhood to older age, could unlock more precise strategies for preventing mental illness and improving mental health care. Throughout the lifespan, external exposome factors – including individual-level and structural exposures – are integrated within the body as the internal exposome. These … Read more