Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise. Now, researchers at University of California San Diego have discovered how healthy stem cells are transformed into cancer stem cells in the earliest stages of the disease. … Read more
TOPLINE: Patients with clinically node-negative breast cancer after neoadjuvant chemotherapy demonstrated low axillary and locoregional recurrence rates after sentinel lymph node biopsy (SLNB) or targeted axillary dissection. METHODOLOGY: More conservative treatment options for women with node-positive breast cancer include SLNB and targeted axillary dissection. However, data comparing patient outcomes after targeted axillary dissection and SLNB … Read more
A new study reveals that even low-dose, chronic exposure to air pollution can trigger liver inflammation, fibrosis, and metabolic disruptions, increasing the risk of fatty liver disease and other hepatic disorders. Study: Mouse study demonstrates liver damage from low-level PM2.5 exposure. Image Credit: Shutterstock AI Generator / Shuttersotck.com A recent study published in the Journal of … Read more
Cancer Care Post-Pandemic: What Has Changed and What’s Next Medscape Source link
A large-scale study reveals azvudine’s comparable efficacy to Paxlovid, fewer adverse effects, and potential antitumor benefits in patients with liver cancer. Study: Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19: a multicenter, retrospective, cohort study. Image Credit: Cryptographer/Shutterstock.com In a recent study published in the Signal Transduction and Targeted Therapy, a … Read more
Patients with low-risk differentiated thyroid cancer show similar outcomes after 5 years regardless of whether they received radioactive iodine following total thyroidectomy, results from a randomized trial show, suggesting patients can be safely spared the additional radioiodine treatment, with some exceptions, including high-risk cases. “This is the first randomized, prospective trial showing that radioiodine is … Read more
Protecting skin from photoaging and photocarcinogenesis requires not only sunscreen — ideally a mineral sunscreen with iron oxide — but also use of topical antioxidants, including polyphenols, and consideration of niacinamide and DNA repair enzymes, according to dermatologists who spoke at the annual Integrative Dermatology Symposium. “We used to talk about protection using UV [ultraviolet] filters, … Read more
Earlier initiation of digital screening mammography at age 40 years leads to substantial healthcare savings by reducing the cost of breast cancer treatment, according to a new cost-effectiveness study. Based on data in Canada for a population-based breast screening program, biennial screening for ages 40-74 years results in fewer deaths, more years of life for … Read more
A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve … Read more
Background and aims The quantitative effects of alcohol consumption on cirrhosis and hepatocellular carcinoma (HCC) in hepatitis B virus (HBV) infection are unknown. This study aimed to establish a dose-dependent model of alcohol consumption on the risks of cirrhosis and HCC. Methods PubMed, Embase, the Cochrane Library, Web of Science, and four Chinese databases were … Read more