Widely used weight-loss and diabetes drugs show clear benefits, but emerging evidence clarifies their side effects, rare risks, and what clinicians should monitor long term. A recent review article published in the Journal of Clinical Investigation summarized the adverse effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual incretin receptor agonists such as tirzepatide. Of … Read more
Diabetic retinopathy develops through complex microvascular damage driven by chronic hyperglycemia, yet traditional risk factors such as disease duration or glycemic control explain only part of individual risk. The retina offers a unique, non-invasive view of microvascular health, where early functional abnormalities may appear before visible retinal lesions. Under normal conditions, retinal vessels automatically constrict … Read more
Could a 45-minute weekly digital coach be the key to reversing diabetes? New study of 130k+ adults shows dramatic risk reduction and remission rates, without pills or extreme diets. Study: Lifestyle Modification in Prediabetes and Diabetes: A Large Population Analysis. Image Credit: RSplaneta / Shutterstock In a recent article published in the journal Nutrients, researchers in the … Read more
TOPLINE: Regular use of glucosamine, a widely used supplement to manage osteoarthritis and joint pain, was linked to reduced risks for both composite microvascular complications and diabetic nephropathy among patients with type 2 diabetes (T2D). METHODOLOGY: Glucosamine, used daily by about 20% of US and Australian adults to treat osteoarthritis and joint pain, has been … Read more
Using real-world data from over 300,000 cases, scientists uncovered a significant link between semaglutide and reported vision problems—raising new concerns about the safety profile of this blockbuster medication. Study: Increased vision impairment reports linked to semaglutide: analysis of FDA adverse event data. Image Credit: memorisz / Shutterstock A team of researchers at the University of Bern, Switzerland, … Read more
TOPLINE: The prevalence of cerebral small vessel disease (CSVD) nearly doubled over 7.5 years in neurologically asymptomatic patients with type 1 diabetes (T1D). The progression of cerebral microbleeds (CMBs), one of the manifestations of CSVD, was associated with baseline systolic blood pressure and A1c among other factors, while the progression of white matter hyperintensities was … Read more
Vision changes are an inevitable part of aging, but why are some more susceptible to age-related eye diseases and why do some individuals experience more severe decline than others? New research from The Jackson Laboratory (JAX) reveals that genetics play a key role in how the eye ages, with different genetic backgrounds influencing retinal aging … Read more