Scientists discover functional role of introns in cells

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to oxidative stress. The segments in question are introns, short sequences of a subset of transfer RNAs, the RNA molecules that help guide assembly … Read more

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics. The technique directs bacteria to produce synthetic disordered proteins that bunch together to form compartments called biological condensates. When these compartments trap mRNA carrying … Read more

Exploring the Link Between Diet and Gene Expression in Fat Tissue

Here is the content you requested: Decoding fat tissue |​ EurekAlert! New research from ⁤the University ⁣of⁤ Delaware ⁢aims to ⁢tackle the issue by investigating obesity at the gene ⁢level.Principal investigator⁤ Ibra Fancher, assistant professor of kinesiology and applied physiology ⁢in UD’s ⁤College ⁣of Health sciences, discovered ⁢significant differences in gene expression in adipose tissue, … Read more

Study examines how diet impacts gene expression in fat tissue

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC. New research from the University of Delaware aims to tackle the issue by investigating obesity at the gene level.  Principal investigator Ibra Fancher, assistant professor of kinesiology and … Read more

Immune gene expression changes in myocardial infarction revealed through bioinformatics

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as potential diagnostic and therapeutic targets. Gene expression data were analyzed from three datasets: GSE29111 and GSE66360, which were combined … Read more

Understanding the role of alternative splicing in cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants. Alterations in exon exclusion, intron retention, or the selection of alternative splice sites modify transcript isoforms, which can consequently affect RNA molecules, including mRNA … Read more

ASU researchers propose a unifying explanation for molecular chaos driving Alzheimer’s disease

In a groundbreaking theory, scientists at Arizona State University’s Biodesign Institute propose a unifying explanation for the molecular chaos driving Alzheimer’s disease. The condition causes widespread disruption of gene behavior, affecting every known neuropathology and clinical manifestation of the disease. According to the analysis, the changes caused by the illness may stem from a breakdown … Read more

New technology unlocks secrets of bacterial gene expression

How do bacteria – harmless ones living in our bodies, or those that cause disease – organize their activities? A new study, combining powerful genomic-scale microscopy with a technical innovation, captured which genes bacteria turn on in different situations and in different spatial environments. The technology, described January 23 in Science, promises to take the study of … Read more

How olive oil bioactives regulate genes linked to insulin resistance

Review explains how olive oil’s bioactive compounds influence key genetic pathways to improve glucose metabolism, reduce inflammation, and support beta-cell function—offering a natural approach to fighting Type 2 Diabetes. ​​​​​​​Review: Impact of Olive Oil Components on the Expression of Genes Related to Type 2 Diabetes Mellitus. ​​​​​​​Image Credit: sebra / Shutterstock In a recent review published in … Read more

Understanding Bone Remodeling: The Role of Fam102a in Osteoblast and Osteoclast Differentiation

Understanding the Role of Fam102a in Bone Remodeling Bones are the dynamic tissue that forms the skeleton, enabling physical movements. They maintain their structural integrity through a process… The post Understanding Bone Remodeling: The Role of Fam102a in Osteoblast and Osteoclast Differentiation appeared first on NewsyList. Source link