Immune scaffold predicts onset weeks early

A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before blood sugar tests turn positive.  Study: Longitudinal monitoring of type 1 diabetes progression to disease onset. Image credit: Halfpoint/Shutterstock.com A recent study published in Science Advances described the application of subcutaneous microporous scaffolds, viz., immunological niches (INs), for … Read more

Soluble E-cadherin drives brain metastasis in aggressive inflammatory breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in patients with aggressive inflammatory breast cancer. The study uncovers a novel role for soluble E-cadherin (sEcad) in promoting tumor invasion while resisting cancer cell death and triggering brain inflammation via the CXCR2 signaling pathway. The results … Read more

Olive oil type matters for cognition and gut health in older adults

A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable links to cognitive aging and gut microbiota profiles over two years. Study: Total and different types of olive oil consumption, gut microbiota, and cognitive function changes in older adults. Image Credit: Mehes Daniel / Shutterstock In a … Read more

How soy and gut microbes alter cancer treatment results

Groundbreaking research reveals how gut microbes and dietary soy can influence the outcome of cancer treatments, paving the way for a new frontier in personalized oncology. Study: Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Image Credit: CI Photos / Shutterstock In a recent study published in the journal Cell, researchers demonstrated that phytochemicals … Read more

Oral 8-aminoguanine protects aging eyes and preserves vision in preclinical study

A breakthrough study shows that a daily oral dose of 8-aminoguanine could safeguard retinal health and slow vision loss in aging, opening new avenues for treating degenerative eye diseases. Study: Oral 8-aminoguanine against age-related retinal degeneration. Image Credit: memorisz / Shutterstock In a recent study in the journal Communications Biology, utilized aged Fischer 344 rats to investigate … Read more

Early Alzheimer’s: Accurate Blood Test Detects Risk

BREAKING: Blood Test Shows Promise for Early Alzheimer’s Detection BREAKING: Blood Test Shows Promise for Early Alzheimer’s Detection A simple blood test is showing potential to transform early… The post Early Alzheimer’s: Accurate Blood Test Detects Risk appeared first on NewsyList. Source link

Blood test pinpoints early Alzheimer’s risk with high accuracy

A simple blood test could revolutionize early Alzheimer’s detection, offering a less invasive and highly accurate tool to identify people at risk before symptoms appear. Study: A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer’s disease. Image Credit: ART-ur / Shutterstock In a recent study … Read more

Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment. Researchers led by Ludwig Lausanne’s Helen Carrasco … Read more

Malaria parasite found to evade the immune system by shutting down key genes

Researchers at Weill Cornell Medicine have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system, sometimes for years. It turns out that the parasite, Plasmodium falciparum, can shut down a key set of genes, rendering itself “immunologically invisible.” “This finding provides another piece of … Read more

New Coronavirus Drug Candidates: Promising Research

A team at UC San Francisco and Gladstone Institutes has developed new drug candidates that show great promise against the virus that causes COVID-19 and potentially other coronaviruses… The post New Coronavirus Drug Candidates: Promising Research appeared first on NewsyList. Source link