This April marks the 50th anniversary of Apple, the U.S. tech behemoth, at a time when artificial intelligence is pushing the Silicon Valley icon to demonstrate its ability to pioneer yet another culture-changing innovation. Steve Jobs, a driven marketing genius, and Steve Wozniak, who invented the Apple computer, revolutionized how people use technology in the … Read more
Step into Jeffrey Lee’s 10,000 sq ft office-slash-warehouse-slash-personal museum in Kwai Chung, and the first problem is purely logistical: where do you look first? The place has the bones of a warehouse – grey carpet, metal racks, long corridors – but it’s lit like a slightly feverish ballroom. The light hits glass, plastic and brass; … Read more
Open this photo in gallery: Kevin Gausman of the Toronto Blue Jays pitches in the second inning of their game against the Athletics at Rogers Centre on Friday.Cole Burston/Getty Images Kevin Gausman set a franchise record with 11 strikeouts on opening day as the Blue Jays kicked off their 50th anniversary season with a 3-2 … Read more
Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS). What makes our body turn against itself? Failure of the immune system to distinguish ‘self’ from ‘non-self’ entities leads to excessive autoimmune responses against self-proteins like myelin, which forms … Read more
In 1986, The New York Times ran a screed against a film-restoration trend gaining steam. In an essay published in the thick of the “colorization” craze of the 1980s, the late critic Vincent Canby argued that the process of altering black-and-white movies with modern visual flourishes “desecrated” those classics, writing that “nobody connected with the original[s]…had anything to do … Read more
For patients undergoing body contouring surgery to remove excess abdominal skin after massive weight loss, use of GLP-1 weight-loss medications may have mixed effects on complication risks, suggests a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer. “As GLP-1 receptor agonist [GLP1ra] medications become increasingly integrated into the care … Read more
Bottom Line: A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient’s risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, with high accuracy. Journal in Which the Study was Published: Cancer Discovery, a journal of the American Association for Cancer Research … Read more
Metabolic-associated steatotic liver disease (MASLD) is a clinically heterogeneous condition with highly variable outcomes affecting more than 30% individuals globally. The disease is conventionally staged by histological progression, ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH) and ultimately fibrosis or cirrhosis. Beyond liver-related outcomes, MASLD significantly elevates the risk of extrahepatic complications, including cardiovascular … Read more
In aggressive lymphomas, inflammatory messengers reprogram the “conductors” of the immune system, causing lymph nodes structure to collapse. A team led by Simon Haas describes in “Nature Cancer” this process for the first time using single-cell and spatial analyses. Lymph nodes are highly organized command centers of the immune system. Within these structures, immune cells … Read more
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