New strategy targets Porphyromonas gingivalis without harming healthy microbes

For years, treating gum disease has meant scraping away plaque, cutting out damaged tissue or turning to antibiotics that kill bacteria indiscriminately. While newer therapies can regenerate lost tissue, doctors still lack a precise way to stop the infection without harming the mouth’s healthy microbiome. New research from the University of Florida College of Dentistry offers … Read more

How are GLP-1 drugs reshaping treatment for obesity, diabetes, and heart disease?

A sweeping Lancet review reveals how modern incretin-based drugs are reshaping treatment for obesity and diabetes, delivering powerful weight loss while simultaneously protecting the heart, kidneys, and metabolic health. Review: GLP-1 receptor agonists and next-generation incretin-based medications: metabolic, cardiovascular, and renal benefits. Image Credit: Gecko Studio / Shutterstock In a recent review published in The … Read more

NIH’s continued investment fuels TMJ pain research

Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported type, followed closely by head and face pain linked to the jaw joint, in the form of temporomandibular joint (TMJ) disorder. While not life-threatening like cancer or infectious disease, chronic pain can dramatically diminish quality of life … Read more

Daily peanut butter intake boosts muscle power in older adults

A clinical trial by researchers at Deakin University’s Institute for Physical Activity and Nutrition (IPAN) in Melbourne, Australia, found that a daily serving of peanut butter significantly boosted muscle power in older adults. The findings were recently published in the international peer-reviewed Journal of Cachexia, Sarcopenia and Muscle (JCSM). The six-month study, known as the … Read more

New guidelines outline comprehensive care for acute pulmonary embolism

Early detection and prompt treatment of acute pulmonary embolism (PE), a sudden and potentially life-threatening blood clot that blocks arteries in the lungs, is critical. Comprehensive recommendations for the evaluation, management and follow-up care for adults with acute PE are detailed in this new clinical practice guideline, published today in the American Heart Association’s flagship … Read more

Review links betel nut addiction to cancer, heart disease, and metabolic risks

Widely used yet often underestimated, betel nut chewing poses significant health risks, and researchers continue to search for effective prevention and treatment strategies. Review: Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies. Image Credit: Radhavar / Shutterstock In a recent study published in the journal Translational Psychiatry, researchers summarized … Read more

Defective fat cells drive metabolic disease in lipodystrophy

Many people may have a dim view of their fat tissue, yet scientists have come to recognize adipose as a necessary and metabolically active organ, carrying out many vital functions within the body. In the case of obesity, too much fat can contribute to conditions such as diabetes and heart disease. Intriguingly, for people with … Read more

Palbociclib Improves Progression‑Free Survival in Double‑Positive Metastatic Breast Cancer: Results from the PATINA Phase 3 Trial

Archyde “`html Palbociclib Extends Progression-Free Survival in Aggressive Breast Cancer, Landmark Study Reveals Table of Contents 1. Palbociclib Extends Progression-Free Survival in Aggressive Breast Cancer, Landmark Study Reveals 2. Understanding the… You can read the full story here: Palbociclib Improves Progression‑Free Survival in Double‑Positive Metastatic Breast Cancer: Results from the PATINA Phase 3 Trial. Source link

Palbociclib improves progression-free survival in HER2 positive breast cancer

PrECOG, LLC, today announced the publication of final results from the pivotal phase 3 PATINA study in the New England Journal of Medicine (NEJM). The study evaluated whether adding palbociclib to anti-HER2 and endocrine therapy, following induction chemotherapy, could delay disease progression in patients with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–positive (HER2+) metastatic … Read more

Reducing alcohol consumption could ease Australia’s cancer burden

Long-term national data reveal that even modest reductions in alcohol consumption across the whole population could prevent thousands of cancer deaths, especially among older Australians. Study: Alcohol consumption and mortality from four alcohol-related cancers in Australia 1950-2018: a time series analysis. Image credit: metodej/Shutterstock.com Population-level reduction of alcohol consumption in Australia could, over the long … Read more